论文部分内容阅读
随着雌激素制品的增多,不同激素替代治疗(HRT)对绝经后妇女的影响成为重要问题。为评估特定HRT配方与上皮性卵巢癌(EOC)危险性的联系进行病例-对照研究。767例研究对象调查前均诊断为EOC 6个月以上,年龄20～69岁。对其中484例浸润性卵巢癌进行分析。对照组年龄20～65岁,经随机数字拨号纳入。研究组484例和926个社区对照按照年龄和居住地匹配。收集两组详细的人口统计学资料和妇产科病史,有无乳腺癌和卵巢癌家庭史。口服避孕药(OC)
With the increase of estrogen products, the impact of different hormone replacement therapy (HRT) on postmenopausal women has become an important issue. A case-control study was conducted to assess the association of specific HRT formulations with the risk of epithelial ovarian cancer (EOC). 767 subjects were diagnosed before the survey as EOC more than 6 months, aged 20 to 69 years. 484 cases of invasive ovarian cancer were analyzed. Control group aged 20 to 65 years old, by random number dialing included. 484 study groups and 926 community controls matched by age and place of residence. Two sets of detailed demographic data and a history of obstetrics and gynecology were collected for family history of breast and ovarian cancer. Oral contraceptives (OC)