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目的:探讨中西医结合治疗糖尿病肾病的临床效果以及安全性,以期为糖尿病肾病的临床治疗找到合适方案。方法:选取150例糖尿病肾病患者,随机分为对照组与观察组,对照组患者行常规西医疗法,观察组患者采用中西医结合治疗,比较两组患者的治疗总有效率,临床症状积分,24h蛋白尿、血肌酐、血尿素氮、餐后血糖等实验室指标。结果:经过治疗,观察组患者总有效率为94.7%,高于对照组的82.4%;观察组患者治疗后24h蛋白尿、血肌酐、血尿素氮、餐后血糖明显低于对照组;观察组患者临床症状积分显著低于对照组,差异均有统计学意义(P<0.05)。两组患者治疗期间及治疗后随访3个月内均未出现明显不良反应。结论:采用中西医结合治疗糖尿病肾病可以提高治愈率,改善患者临床症状及实验室指标,并无明显不良反应发生,有确切的疗效及安全性。
Objective: To explore the clinical efficacy and safety of integrated traditional Chinese and western medicine in the treatment of diabetic nephropathy, in order to find a suitable plan for the clinical treatment of diabetic nephropathy. Methods: 150 patients with diabetic nephropathy were randomly divided into control group and observation group. Patients in control group underwent routine Western medical therapy. Patients in observation group were treated with combination of TCM and Western medicine. The total effective rate, clinical symptom scores, Proteinuria, serum creatinine, blood urea nitrogen, postprandial blood glucose and other laboratory indicators. Results: After treatment, the total effective rate in observation group was 94.7%, which was higher than that in control group (82.4%). Proteinuria, serum creatinine, blood urea nitrogen and postprandial blood glucose in observation group were significantly lower than those in control group The clinical symptom score of patients was significantly lower than that of the control group, the differences were statistically significant (P <0.05). Two groups of patients during treatment and follow-up within 3 months after treatment showed no significant adverse reactions. Conclusion: The treatment of diabetic nephropathy by Integrative Medicine can improve the cure rate, improve the clinical symptoms and laboratory parameters of patients without obvious adverse reactions and have definite curative effect and safety.