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非糜烂性反流病(non-erosive reflux disease,NERD)是胃食管反流病(gastroesophageal reflux disease,GERD)的一种亚型,临床上有反酸、烧心、反食、胸痛、咳嗽等典型或不典型反流症状,但胃镜检查无食管黏膜糜烂、溃疡等内镜下表现。NERD约占GERD的50%~70%~([1]),门诊就诊患者众多,由于其食管阴性的内镜下表现,以及功能性烧心、心源性胸痛等疾病也可具有GERD症状,使其诊断及鉴别诊断存在一定的难度。Gerd Q量表、24 h食管pH监测等是诊断GERD的检查方法,但由于一些原因
Non-erosive reflux disease (NERD) is a subtype of gastroesophageal reflux disease (GERD), which is clinically known as reflux, heartburn, anti-reflux, chest pain and cough Or atypical reflux symptoms, but endoscopy without esophageal mucosal erosion, ulcers and other endoscopic performance. NERD accounts for about 50% -70% of GERD ([1]). There are a large number of outpatients, because of their esophageal negative endoscopic findings, and functional heartburn and cardiogenic chest pain and other diseases may also have GERD symptoms The diagnosis and differential diagnosis there is a certain degree of difficulty. The Gerd Q scale, 24-h esophageal pH monitoring, etc. are diagnostic tests for GERD but for some reason