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自1958年第一个β-肾上腺素能受体阻断剂二氯异丙肾上腺素(Dichloroisoprenaline)问世以来,这一类药物引起人们极大的重视,新药不断出现,药理学研究不断深入,临床应用范围日益扩大,目前已广泛用于治疗心律失常、高血压、心绞痛等疾病.近年来不少报导认为,这一类药物对某些中枢神经系统疾病也有一定价值.本文目的在于概述以心得安为代表的某些β-肾上腺素能受体阻断剂(以下简称β-阻断剂)的中枢效应及在精神、神经系统疾病中的应用.
Since the advent of the first β-adrenergic receptor blocker, Dichloroisoprenaline, in 1958, this group of drugs has drawn great attention. New drugs are constantly emerging, pharmacological research continues to deepen, and clinical It has been widely used in the treatment of arrhythmia, hypertension, angina pectoris and other diseases in recent years, many reports believe that this type of medicine for some diseases of the central nervous system also has some value.This paper aims to outline the peace of mind As the representative of some β-adrenergic receptor blockers (hereinafter referred to as β-blockers) central effect and in the mental, nervous system diseases.