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目的为难治性癫(IE)患者的外科治疗制定循证方案。方法针对1例IE患者诊治中的临床问题,检索临床指南、系统评价、m eta分析及随机对照试验,并评价其质量,判断其真实性、适用性,获取最佳证据并应用于临床。结果共检索到3篇指南、5篇系统评价和1篇结局研究,分析结果表明IE从定义到诊治都还存在着许多争议。结合患者情况,应用循证证据治疗,随访半年的疗效较好。结论循证治疗可以提高患者疗效,但仍然缺乏充分的证据。
Objective To develop an evidence-based protocol for the surgical treatment of refractory epilepsy (IE) patients. Methods According to the clinical problems in the diagnosis and treatment of 1 case of IE, the clinical guidelines, systematic reviews, m eta analysis and randomized controlled trials were searched and evaluated. The authenticity and applicability of the method were evaluated and the best evidence was obtained for clinical application. Results A total of 3 guidelines, 5 systematic reviews and 1 outcome study were retrieved. The results showed that there were still many controversies over the definition, diagnosis and treatment of IE. Combined with the patient’s condition, the application of evidence-based evidence of treatment, follow-up of six months of good effect. Conclusion Evidence-based treatment can improve the efficacy of patients, but there is still a lack of sufficient evidence.