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母婴传播是乙型肝炎的主要传播方式,孕妇HBsAg和HBeAg双阳性者所生婴儿,1岁时有90～100％已受感染,因此对新生儿采用乙肝疫苗作主动免疫,是今后控制人群中乙肝感染的重要措施。本文以乙肝基因重组疫苗和血源疫苗对63例HBsAg、HBeAg阳性产妇所生的新生儿进行接种观察免疫阻断HBV围产期传播的效果,现将结果报告如下。材料与方法一、观察对象本文63例选自1985年11月至1986年11月,在福州市区5所医院及三明市医院6个单位筛检产前门诊的孕妇,凡HBsAg、HBeAg双阳性产妇所产的新生儿按随机法分成A、B、C、D4组作为乙肝疫苗接种的观察对象。二、疫苗与免疫方案我们将接种Merck乙肝基
Mother-to-child transmission is the major mode of transmission of hepatitis B, and babies born to pregnant women with HBsAg and HBeAg double positives have been infected at 90 to 100% at 1 year of age. Therefore, the use of hepatitis B vaccine for neonatal immunization is the active control of the future population In hepatitis B infection important measures. In this paper, hepatitis B gene recombinant vaccine and blood-borne vaccine 63 cases of HBsAg, HBeAg-positive mothers of newborns were vaccinated to observe the effect of blocking the perinatal HBV transmission by immunization, the results are reported as follows. Materials and methods First, the observed object 63 cases selected from November 1985 to November 1986, in Fuzhou City, 5 hospitals and Sanming City Hospital, 6 units of prenatal screening of pregnant women, where HBsAg, HBeAg double positive Neonates born in mothers were randomly divided into A, B, C, D4 group as hepatitis B vaccination observation object. Second, the vaccine and immunization program We will vaccinate Merck hepatitis B base