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患者和方法 Sjogren氏病31例(女30,男1,21～73岁),慢性腮腺炎12例(女10,男2,16～80岁)。经实验室和免疫学检查,下唇粘膜小涎腺活检,X线造影等明确诊断。病史1～24年。对照组是5名健康人(18～20岁)。进行口腔检查;测定用1％毛果芸香硷刺激前、后唾液10分钟分泌量;计算1cm~2下唇粘膜有功能的小涎腺数;进食后2～2.5小时收集唾液,并用6ml生理盐水含漱取得口腔灌洗液,唾液和灌洗液离心后取沉渣涂片、染色、镜检,计算白细胞和上皮细胞数,进行上皮细胞分型:表层,中层,基底旁和基底层细胞。结果健康人,10分钟唾液分泌量,刺激前2.8±0.1ml,刺激后增至7.5±0.1ml。1cm~2唇粘膜有功能的小涎腺数7.3±0.5。唾液和口腔灌洗液,中性白
Patients and Methods Thirty-one Sjogren's disease patients (30 males and 1,21 to 73 years old) and 12 chronic males (10 males and 2 to 16 years old) were included. The laboratory and immunological examination, the lower lip mucosa salivary gland biopsy, X-ray angiography and other clear diagnosis. A history of 1 to 24 years. The control group was 5 healthy people (18 to 20 years old). Oral mucosa of 1cm ~ 2 to determine the number of small salivary glands function; 2 ~ 2.5 hours after eating saliva, and with 6ml of normal saline After rinsing, the lavage fluid was taken into the oral cavity, and the smear of saliva and lavage fluid was centrifuged. Staining and microscopic examination were carried out to count the number of leukocytes and epithelial cells. Epithelial cell types were classified as epithelial cells, middle layers, paracancer cells and basal cells. The results of healthy people, 10 minutes saliva secretion, 2.8 ± 0.1ml before stimulation, increased to 7.5 ± 0.1ml after stimulation. 1cm ~ 2 lip mucosal function of the small salivary glands 7.3 ± 0.5. Saliva and oral lavage fluid, neutral white