Study on the Synthesis of Metabolite CM2 of Clausenamide

• 出 处: Chinese Chemical Letters
• 发表日期: 2003年04期
• 关键词: ketone constants ambient bioactivity optically coincide Figure neutral likely ac

Synthesis of the optically active metabolite of clausenamide CM2 (3, 5-dihydroxy- 5-(a-hydroxylbenzyl)-1-methyl-4-benzylpyrrolidin-2-one) from 3-O-acetyl- clausenamide was described.

Synthesis of the optically active metabolite of clausenamide CM2 (3, 5-dihydroxy 5- (a-hydroxylbenzyl) -1 -methyl- 4-benzylpyrrolidin-2-one) from 3-O-acetyl-clausenamide was described.