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目的了解海珠区1～59岁人群病毒性肝炎流行现状,为制定防控策略提供依据。方法采取多阶段随机抽样方法,抽取1～59岁常住居民,对基本情况、甲肝及乙肝疫苗接种情况等进行问卷调查,并采集静脉血用ELISA法检测甲肝、乙肝、丙肝及戊肝血清学指标。结果共调查597人,全区1～59岁人群抗-HAV标化流行率77.3%,HBV标化流行率40.6%,抗-HCV流行率为0,抗-HEV标化流行率8.2%;抗-HAV和HBV流行率均随年龄增长而升高;抗-HAV、HBV和抗-HEV标化流行率性别差异无统计学意义。各型肝炎存在混合感染,两型混合感染占27.0%,3型混合感染占4.2%。HBVM模式有10种,以单抗-HBs阳性最多(47.1%),其次为5项全阴(22.5%)。结论海珠区1～59岁人群病毒性肝炎流行的主要类型是HAV和HBV,应继续加强对甲、乙型肝炎的防控力度。
Objective To understand the prevalence of viral hepatitis among people aged 1- 59 years in Haizhu District and to provide evidence for the development of prevention and control strategies. Methods A multistage random sampling method was adopted to select the residents aged from 1 to 59 years. The basic conditions, hepatitis A and hepatitis B vaccination were surveyed by questionnaire, and the venous blood samples were collected for the detection of serological markers of hepatitis A, hepatitis B, hepatitis C and hepatitis E by ELISA . Results A total of 597 people were surveyed. The prevalence of anti-HAV, anti-HCV and anti-HCV was 77.3%, 40.6%, anti-HCV and anti-HCV respectively -HAV and HBV prevalence increased with age; gender-specific prevalence of anti-HAV, HBV and anti-HEV had no statistical significance. Mixed infection of various types of hepatitis, two mixed infections accounted for 27.0%, 3 mixed infections accounted for 4.2%. There are 10 kinds of HBVM patterns, with the highest number of McAb-HBs positive (47.1%), followed by 5 all-yin (22.5%). Conclusions The main types of viral hepatitis in HCC patients from 1 to 59 years old are HAV and HBV. The prevention and control of hepatitis A and B should be further strengthened.