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目的比较胰酶肠溶胶囊和复方阿嗪米特肠溶片治疗酒精性脂肪肝合并消化不良的疗效。方法 126例酒精性脂肪肝合并消化不良患者,随机分成3组:C组,40例,单用多烯磷脂酰胆碱作为对照;A组,45例,加用胰酶肠溶胶囊;B组,41例,加用复方阿嗪米特肠溶片;服药2周后观察疗效。结果 B组治疗腹胀的有效率高于A组(93.33%vs.66.66%)(P<0.05),A组治疗粪便异常和排气增多的疗效均优于B组(95.55%vs.78.04%和92.68%vs.75.67%)(P<0.05);A、B两组治疗食欲减退的疗效相仿(78.57%vs.76.92%)(P>0.05);A、B两组的疗效均优于C组(P<0.05)。结论胰酶肠溶胶囊和复方阿嗪米特肠溶片治疗酒精性脂肪肝合并消化不良各有特色,应按需用药。
Objective To compare the efficacy of pancreatic enteric-coated capsules and compound azamet enteric-coated tablets in the treatment of alcoholic fatty liver complicated with dyspepsia. Methods A total of 126 alcoholic fatty liver disease patients with dyspepsia were randomly divided into three groups: group C (n = 40), polyene phosphatidylcholine alone (n = 45), group A , 41 cases, plus compound azinamid enteric-coated tablets; 2 weeks after treatment efficacy. Results The effective rate of treating abdominal distension in group B was higher than that of group A (93.33% vs.66.66%) (P <0.05). The efficacy of treating fecal abnormalities and excretion in group A was better than that of group B (95.55% vs.78.04% and 92.68% vs.75.67%, respectively) (P <0.05). The curative effect of treatment of loss of appetite in groups A and B were similar (78.57% vs.76.92%) (P> 0.05) (P <0.05). Conclusion Pancreatic enteric-coated capsules and compound azinamid enteric-coated tablets for treatment of alcoholic fatty liver with indigestion have their own characteristics, should be on demand medication.