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目的：客观了解人群麻疹疫苗免疫接种率及血清麻疹抗体阳性率，为制定麻疹控制策略提供依据。方法：应用酶联免疫吸附试验（ELISA）法对3455名8月龄以上健康人群血标本进行麻疹IgG抗体水平检测并调查麻疹疫苗接种情况。结果:调查目标人群3455人，接种麻疹疫苗2800人，接种率81.04 %，10岁以下年龄组儿童疫苗调查接种率均在95%以上，10岁以上人群调查接种率在4.25-81.6%之间；检测血清标本3455份，麻疹IgG抗体阳性3261份， 阳性率94.38%；不同年龄组之间麻疹抗体阳性率差异有统计学意义（×2＝75.94 p<0.01）；不同地区健康人群麻疹抗体阳性率差异有统计学意义（×2＝106.16 p<0.01）；有无免疫史、有无麻疹患病史人群麻疹抗体阳性率差异无统计学意义（ ×2＝0.021 75.94，×2＝ 0.032 p>0.05 ）。结论：曲靖市健康人群麻疹疫苗调查免疫接种率81.04 %，血清抗体阳性率94.38%，人群建立了良好的免疫屏障；各地麻疹疫苗接种管理工作发展不平衡；不同地区存在薄弱环节，疫苗接种痕迹资料归档保存管理工作不规范。加强免疫规划工作人员业务技术培训，加强检查指导，制定工作职责和可行的奖惩措施、提高工作人员责任心是提高免疫接种工作质量的关键。
OBJECTIVE: To objectively understand the population immunization rate of measles vaccine and the positive rate of serum measles antibody in order to provide evidence for the development of measles control strategy. Methods: The blood samples of 3455 healthy people over 8 months of age were tested for measles IgG antibody level by enzyme-linked immunosorbent assay (ELISA) and the measles vaccination situation was investigated. Results: The survey target population 3455 people, 2800 measles vaccination, vaccination rate of 81.04%, children under 10 years old vaccination survey vaccination rates were above 95%, 10 years of age population survey vaccination rate between 4.25-81.6%; The positive rate of measles IgG antibody in 3455 serum samples was 3261, with a positive rate of 94.38%. The positive rate of measles antibody in different age groups was significantly different (χ 2 = 75.94 p <0.01). The positive rate of measles antibody in healthy population The difference was statistically significant (χ2 = 106.16 p & lt; 0.01). There was no history of immunization. There was no significant difference in the positive rate of measles antibody between the groups with or without measles history (× 2 = 0.021 75.94, × 2 = 0.032 p> 0.05 ). Conclusion: The immunization coverage rate of measles vaccine in healthy population in Qujing was 81.04%, the positive rate of serum antibody was 94.38%. The immune barrier was established in the population. The development of measles vaccination in various regions was not balanced. There were weak links in different areas, Archive preservation management is not standardized. Strengthening the technical training of immunization program staff, strengthening inspection and guidance, setting work responsibilities and feasible reward and punishment measures, and improving staff sense of responsibility are the keys to improving the quality of immunization work.