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本文报道了69例抗生素诱发的难辨菌性肠炎,其诊断标准是:腹泻前使用了某种抗生素、典型临床表现及粪便中分离出难辨菌,并用组织培养证实有可中和的细胞毒素。77%经过治疗后恢复,14.5%死于并发症,如肠麻痹和梗阻,肠穿孔及休克,并讨论了诊断与治疗。1977～1978年由Bartlett等证实抗生素诱发性肠炎,其中也包括伪膜性肠炎,是由难辨梭状芽胞杆菌(简称难辨菌)所引起。本文介绍了协和医院1982年10月～1984年4月69例抗生素诱发的难辨菌性肠炎(Antibiotic-associated Clostridium difficile Colitis简称AAC)的临床症状、诊断及治疗。
This article reports 69 cases of antibiotic-induced difficile bacterial enteritis, the diagnostic criteria are: the use of a certain antibiotics before diarrhea, the typical clinical manifestations and stool separation of hard-to distinguish bacteria, and tissue culture confirmed that there is a neutralizable cytotoxic . 77% recovered after treatment, 14.5% died of complications such as intestinal paralysis and obstruction, intestinal perforation and shock, and discussed diagnosis and treatment. 1977-1978 by Bartlett et al confirmed antibiotic-induced enteritis, which also includes pseudomembranous enteritis, is caused by Clostridium difficile (referred to as Difficult to distinguish bacteria). This article describes the clinical symptoms, diagnosis and treatment of 69 cases of antibiotic-induced Clostridium difficile Colitis (AAC) from October 1982 to April 1984 in Union Hospital.