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AIM:To characterize the increasing incidence and geographic variation of acute diverticulitis.METHODS:Using the nationwide inpatient sample (NIS) we identified a cohort who had been admitted with diverticulitis between 1998 and 2005.We calculated age-,sex-,and region-specific rates of hospitalizations for diverticulitis over time.RESULTS:The age-adjusted hospitalization rate for diverticulitis increased from 61.8 per 100000 to 75.5 per 100 000 between 1998 and 2005,and increased similarly in both sexes.Diverticulitis-associated admissions were male-predominant in those younger than age 45 years but were female-predominant thereafter.Admission rates increased the most among those<45 years,while remaining unchanged for those≥65 years.By 2005,the majority of hospitalized patients were<65 years.Age-adjusted rates of diverticulitis-associated hospitalizations were lower in the West(50.4/100000) compared to the Northeast(77.7/100000),South (73.9/100000),and Midwest(71.0/100000).CONCLUSION:Diverticulitis-associated hospitalizations have steeply risen,especially in young adults.These epidemiological trends vary by geographic region and warrant further investigation into potential dietary and environmental etiologies.
A characterizing the increasing incidence and geographic variation of acute diverticulitis. METHODS: Using the nationwide inpatient sample (NIS) we identified a cohort who had been admitted with diverticulitis between 1998 and 2005. We calculated age-, sex-, and region- specific rates of hospitalizations for diverticulitis over time .RESULTS: The age-adjusted hospitalization rate for diverticulitis increased from 61.8 per 100000 to 75.5 per 100 000 between 1998 and 2005, and increased similarly in both sexes. Liverticulitis-associated admissions were male-predominant in those younger than age 45 years but were female-predominant thereafter.Admissions rates increased the most among those <45 years, while remaining unchanged for those≥65 years.By 2005, the majority of hospitalized patients were <65 years. Age-adjusted rates of diverticulitis-associated hospitalizations were lower in the West (50.4 / 100000) compared to the Northeast (77.7 / 100000), South (73.9 / 100000), and Midwest (71.0 / 100000) Diverticulitis-associated hospitalizations have steeply risen, especially in young adults. The epidemiological trends vary by geographic region and warrant further investigation into potential dietary and environmental etiologies.