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为寻找新的抗心肌缺氧药物,我们研究了谷氨酸钠对正常家兔急性窒息后心脏电活动的影响。 方法:挑选健康家兔27支,性别不拘,体重2.2~2.8kg,用20%乌拉坦溶液(5ml/kg)耳静脉麻醉,切开气管,插气管套管备阻塞用。17只为对照组,只行急性窒息;10只为药物组,在窒息前2分钟开始静滴谷氨酸钠(100mg/kg,加入100ml生理盐水中)用心电图机记录Ⅱ导联急性窒息前、后的心电图。窒息后最初15分钟每隔0.5分钟,15~20分钟每隔1
In search of a new anti-myocardial oxygen drug, we investigated the effect of sodium glutamate on cardiac electrical activity after acute asphyxia in normal rabbits. Methods: Twenty-seven healthy rabbits were selected. The patients were randomly divided into two groups, weighing 2.2-2.8kg. The rabbits were anesthetized with 20% urethane solution (5ml / kg). The trachea was opened and the trachea was cannulated for obstruction. 17 as the control group, only acute asphyxia; 10 as the drug group, intravenous glutamate (100mg / kg, 100ml normal saline) started 2 minutes before asphyxia recorded by electrocardiogram Ⅱ lead before acute asphyxia After the electrocardiogram. Asphyxiation after the first 15 minutes every 0.5 minutes, every 15 to 20 minutes