Role of stromal cell-derived factor la pathway in bone metastatic prostate cancer

• 作 者: Nisha Gupta Dan G. Duda
• 机 构: SteeleLaboratoriesforTumorBiology
• 出 处: 生物医学研究杂志：英文版
• 发表日期: 2016年3期
• 关键词: 基质细胞衍生因子 前列腺癌 通路 LA CXCR4 相互作用 肿瘤细胞 SDF SDF 1 a CXCR4 bone metastasis prostat
• 基金项目: supported by NIH grants R01-CA159258 and P01-CA080124,American Cancer Society Grant 120733-RSG-11-073-01-TBG

Metastatic prostate cancer is one of the leading causes of cancer-related death in men.The primary site of metastasis from prostate cancers is the bone.During the last decade,multiple studies have pointed to the role of the stromal cell-derived factor 1 a