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本文报道口服吡美诺(Pirmenol)对室性心律失常的长期(3年)疗效。 12例曾用多种抗心律失常药无效或有严重副作用的室性早搏患者,口服吡美诺每日200～500mg。根据24小时动态心电图评价疗效。凡室性早搏次数减少>75％者列为有效。平均随访33±4(24～36)个月,7例(58％)有效;2例(17％)部分有效;3例(25％)无效。起始量每日317±94mg,末次随访时每日375±97mg;有效者每日343±113mg,
This article reports the long-term (3-year) efficacy of oral Pirmenol on ventricular arrhythmias. Twelve patients with ventricular premature beats who had multiple antiarrhythmic drugs that were ineffective or had severe side effects received oral pimecline 200 to 500 mg daily. According to 24-hour Holter assessment of efficacy. Where the number of premature ventricular contractions decreased by> 75% were valid. The average follow-up was 33 ± 4 (24-36) months, with 7 (58%) effective; 2 (17%) partially effective; and 3 (25%) ineffective. The initial amount of daily 317 ± 94mg, the last follow-up daily 375 ± 97mg; the effective daily 343 ± 113mg,