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作者用雄性大鼠研究了在振动、噪音、热和铅单独和联合作用后的肝脏变化。将动物分成8个组(第1组振动—100赫兹、0.1毫米振幅;第2组噪音—105分贝;第3组受热—35℃;第4组每天用醋酸铅水溶液染毒;第5组振动和噪音;第6组振动和热;第7组振动和铅;第8组对照),每天暴露到这些因素2小时,连续10天。测定指标有肝组织匀浆中琥珀酸脱氢酶(Suc DH)、LDH、ATP酶、可溶性蛋白质(Sp)和巯基(—SH)含量,并用显微镜检查了肝脏形态学变化。
The authors used a male rat to study liver changes after vibration, noise, heat and lead alone and in combination. The animals were divided into 8 groups (Group 1 vibration -100 Hz, 0.1 mm amplitude; Group 2 noise -105 dB; Group 3 heat -35 ° C; Group 4 daily exposure to aqueous lead acetate solution; Group 5 vibration and Noise; Group 6 vibration and heat; Group 7 vibration and lead; Group 8 control) were exposed to these factors daily for 2 hours for 10 consecutive days. The indexes of liver homogenate were Suc DH, LDH, ATPase, soluble protein (Sp) and sulfhydryl (-SH) in liver homogenate. The morphological changes of liver were observed with microscope.