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以茄尼醇为原料与4种不同的酸酐反应,然后再与N-烷羟基-替加氟反应,得到12个新的目标化合物.其结构经IR,1H NMR,MS确认.初步的体外抗肿瘤实验结果表明,目标化合物具有一定抗肿瘤活性.
The reaction of solanesol with four different anhydrides and subsequent reaction with N-alkyloxy-tegafur gave 12 new target compounds, which were confirmed by IR, 1H NMR and MS. Tumor test results show that the target compound has a certain anti-tumor activity.