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目的:观察采用加味四君固本汤联合化疗对肺癌患者生活质量及不良反应的影响、方法:100例中晚期肺癌患者随机分为观察组与对照组,2组各50例。对照组采用NP方案常规化疗治疗;观察组在对照组治疗基础上加服加味四君固本汤治疗结果:总缓解率(CR+PR)观察组60.0%,对照组30.0%,2组比较,差异有显著性意义(P<0.05)。治疗前2组生活质量评分比较无差异(P>0.05),治疗后观察组生活质量评分显著高于对照组,差异有显著性意义(P<0.05)。不良反应总发生率观察组70.0%,对照组98.0%,2组比较,差异有显著性意义(P<0.05)。结论:加味四君固本汤联合化疗治疗肺癌效果显著,可提高患者的生活质量,降低不良反应发生率。
OBJECTIVE: To observe the effects of modified four-jun guben decoction combined with chemotherapy on the quality of life and adverse reactions in patients with lung cancer.Methods: One hundred cases of advanced lung cancer were randomly divided into observation group and control group, 50 cases in each group. The control group was treated with conventional chemotherapy with NP regimen. The observation group was treated with modified Sijun Guben decoction on the basis of the control group: the total CR rate was 60.0% in the observation group and 30.0% in the control group, The difference was significant (P <0.05). There was no significant difference in quality of life between the two groups before treatment (P> 0.05). After treatment, the quality of life in the observation group was significantly higher than that in the control group (P <0.05). The total incidence of adverse reactions in the observation group 70.0%, 98.0% in the control group, the two groups, the difference was significant (P <0.05). Conclusion: Modified Sijun Guben Decoction combined with chemotherapy has significant effect on lung cancer, which can improve patients’ quality of life and reduce the incidence of adverse reactions.