Globoside accelerates the differentiation of dental epithelial cells into ameloblasts

• 作 者: Takashi Nakamura Yuta Chiba Ma
• 机 构: DivisionofMolecularPharmacologyandCellBiophysics,DivisionofPediatricDentistry,DivisionofDevelopmenta
• 出 处: 国际口腔科学杂志：英文版
• 发表日期: 2016年4期
• 关键词: 上皮细胞 成釉细胞 细胞分化 红细胞 P38丝裂原活化蛋白激酶 糖苷 神经营养因子 调控作用 ameloblast differentiation enam
• 基金项目: This work was supported by JSPS KAKENHI from the Japan Society for the Promotion of Science and the Ministry of Education （ 15H05032 and 15K 15752 to Takashi Nakamura and 26253092 to Satoshi Fukumoto）

Tooth crown morphogenesis is tightly regulated by the proliferation and differentiation of dental epithelial cells. Globoside(Gb4),a globo-series glycosphingolipid, is highly expressed during embryogenesis as well as organogenesis, including tooth develop