Sulbactam protects hippocampal neurons against oxygen-glucose deprivation by upregulation of GLT-1 v

• 作 者: QI Jie ZHANG Jing-ge ZHANG Min HU Yu-yan LI Wen-bin
• 机 构: Department of Pathophysiology,Hebei Medical University,Aging and Cognition Neuroscience Laboratory o
• 出 处: 中国病理生理杂志
• 发表日期: 2015年10期

The present study was undertaken to investigate the role of p38 MAPK on the upregulation of GLT-1 induced by sulbactam during the mimic ischemic neuronal protection by neuron-astrocyte co-culture and astrocyte culture of neonatal rats.Following with 48 h sulbactam incubation or not,the culture was under 2 h oxygen glucose deprivation(OGD),and then the medium was replaced by the ba-

The present study was undertaken to investigate the role of p38 MAPK on the upregulation of GLT-1 induced by sulbactam during the mimic ischemic neuronal protection by neuron-astrocyte co-culture and astrocyte culture of neonatal rats. Following with 48 h sulbactam incubation or not , the culture was under 2 h oxygen glucose deprivation (OGD), and then the medium was replaced by the ba-