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重度预痫患者可能出现凝血系统的变化,及由于肾功能变化引起的高尿酸血症。上两项变化,主要反映疾病的严重性。Howie等描述了由血纤维蛋白/纤维蛋白之降解产物(FDP)的浓度、Ⅷ因子的活性和血小板计数等得出的血凝固指数、Redman等报导大部高血压患者的血清尿酸盐浓度和胎儿预后有关。作者将Howie的血凝变化和妊娠晚期合并高血压患者的血清尿酸盐浓度进行比较、同时检查了基础肾功能。病人和方法对单胎晚期妊娠住院46名妇女进行研究。按下表列举的标准分组。有10例重度预痫,18例轻度预
Patients with severe pre-eclampsia may have changes in the coagulation system and hyperuricemia due to changes in renal function. The two major changes reflect the seriousness of the disease. Howie et al. Described the blood coagulation index derived from the concentration of fibrin / fibrin degradation products (FDP), the activity of factor VIII and platelet count, etc. Redman et al. Reported serum urate concentrations in most hypertensive patients and Fetal prognosis. The authors compared Howie’s changes in hemagglutination with serum urate concentrations in patients with late-stage pregnancy-associated hypertension and examined underlying renal function. Patients and Methods A study of 46 women hospitalized for singletonic late pregnancy. Follow the standard groupings listed in the table below. There are 10 cases of severe pre-eclampsia, 18 cases of mild pre-treatment