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酪氨酸酶是黑素代谢的关键酶,其活性改变可导致黑素合成代谢的障碍。为此,我们从中医治疗白癜风的文献中,选出 56种常用的中药,观察其对酪氨酸酶的影响,在此基础上以棕色豚鼠为动物模型进行动物致色素实验,希望从中能筛选出作用更好的药物。 一、材料与方法 (一 )材料:
Tyrosinase is a key enzyme for the metabolism of melanin, and its altered activity can lead to impaired melanin anabolism. To this end, we selected 56 kinds of commonly used Chinese medicines from the literature on the treatment of vitiligo by Chinese medicine and observed their effects on tyrosinase. Based on this, we used brown guinea pigs as animal models to conduct animal pigmentation experiments. Out better drugs. I. Materials and Methods (1) Materials: