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目的:探讨口服铁剂和静脉注射铁剂治疗肾性贫血的效果。方法:分别抽取2010年8月以来湖南省几大医院采用口服铁剂、静脉注射铁剂治疗肾性贫血患者的临床资料各24例,在对48例患者完成半年临床观察后,以铁剂治疗前后两组患者的血红蛋白和红细胞比容变化以及两组患者治疗的好转程度来衡量治疗效果,以有效率作为效果指标。结果:半年的研究结果表明,口服组和静脉组治疗总有效率分别为66.67%和91.67%,差异有统计学意义(P<0.05)。结论:两组比较,静脉组在治疗肾性贫血中的疗效比口服组要好,静脉注射的治疗方法不仅能及时有效地补充肾性贫血患者所需的铁剂,使贫血状况改善,而且还能增强EPO效应,临床上值得推荐。
Objective: To investigate the effect of oral iron and intravenous iron on renal anemia. Methods: The clinical data of 24 patients with renal anemia treated by oral administration of iron and intravenous injection of iron were collected from several hospitals in Hunan Province since August 2010, respectively. Twenty-four patients (48 patients) completed clinical observation and received iron treatment Before and after the two groups of patients with hemoglobin and hematocrit changes and the improvement of the two groups of patients treated to measure the effect of treatment, the efficiency as an indicator of effectiveness. Results: The results of six months showed that the total effective rates of oral and intravenous groups were 66.67% and 91.67%, respectively, with significant difference (P <0.05). CONCLUSIONS: In both groups, the efficacy of intravenous group in treating renal anemia was better than that of oral group. The intravenous injection therapy not only can promptly and effectively replenish the iron needed by patients with renal anemia, but also can improve anemia, Enhanced EPO effect, clinically worth recommending.