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[目的]研究放射性同位素氡及其子体对造血系统的影响及远离氡污染地区后外周血的改变。[方法]1993年采用人工方法对居住在氡及其子体高暴露地区的730例人群进行血红蛋白(HB)测定、白细胞(WBC)计数与白细胞分类计数,并与2005年对该人群追踪调查的253例复检结果进行比较。[结果]1993年氡及其子体高暴露人群730例有血常规异常者233例,其中HB异常者135例,降低者26例,增高者109例;WBC异常98例,降低者86例,增高者12例;不同性别、年龄间分别进行χ2检验;1993与2005年进行比较,HB男性、女性增高异常率1993年明显高于2005年(χ2分别为7.01,2.78,P﹤0.1);WBC男性、女性降低异常率1993年明显高于2005年(χ2分别为11.16、6.46,P﹤0.05)。WBC分类调查结果1993年与2005年比较,N、L、M、E均有统计学差异(P﹤0.05)。[结论]长期生活于氡及其子体高暴露地区的人群,可能引起骨髓造血功能抑制造成贫血、WBC减少或引起骨髓红系过度增生造成HB增高等造血系统异常的改变,因此不能忽视氡对造血系统的影响,应引起重视。
[Objective] The research aimed to study the influence of radon and its daughters on the hematopoietic system and the changes of peripheral blood in far away from radon-contaminated area. [Method] In 1993, the determination of hemoglobin (HB), white blood cell count (WBC) and white blood cell count of 730 human population living in high exposure areas of radon and its progeny were manually measured and compared with the 253 Cases of re-examination results for comparison. [Results] In 1993, there were 233 cases of abnormal blood samples in 730 cases with high exposure to radon and its daughters, among which 135 cases were abnormal HB, 26 cases were reduced, 109 cases were higher; 98 cases were abnormal WBC, 86 cases were decreased (N = 12) .χ 2 test was performed in different sex and age groups. Compared with 2005, the abnormality rate of HB male and female was significantly higher in 1993 than in 2005 (χ2 = 7.01, 2.78, P < , And the rate of female abnormality reduction in 1993 was significantly higher than that in 2005 (χ2 = 11.16 and 6.46, respectively, P <0.05). WBC classification survey results 1993 compared with 2005, N, L, M, E were statistically significant (P <0.05). [Conclusion] People living in areas with high exposure to radon and its progeny for a long time may cause hematopoietic suppression of bone marrow to cause anemia, WBC to reduce or cause abnormal proliferation of hematopoietic system such as increased HB caused by hyperplasia of bone marrow, so we can not ignore the effect of radon on hematopoiesis The impact of the system should be taken seriously.