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目的:分析依帕司他与丹红注射液用于糖尿病周围神经病变(DPN)治疗中的临床效果。方法:选取北京市朝阳区劲松社区卫生服务中心2015年1月至2015年12月收治的60例DPN患者,运用双色球随机分组法分为观察组(n=30)和对照组(n=30),对照组患者采用依帕司他治疗,观察组患者采用依帕司他联合丹红注射液治疗,讨论两组患者治疗效果。结果:观察组患者治疗有效率93.33%,高于对照组的73.33%,组间比较,差异具有统计学意义(P<0.05);治疗后观察组患者感觉神经传导速度(SNCV)、运动神经传导速度(MNCV)均高于对照组,差异具有统计学意义(P<0.05)。结论:对DPN患者,依帕司他与丹红注射液联合用药,可有效缓解临床症状,改善运动和感觉传导速度,加快康复速度。
Objective: To analyze the clinical effect of epalrestat and Danhong injection in the treatment of diabetic peripheral neuropathy (DPN). Methods: Sixty patients with DPN admitted from Jinsong Community Health Service Center in Chaoyang District of Beijing from January 2015 to December 2015 were divided into observation group (n = 30) and control group (n = 30) by bicolor ball randomization method. , The control group patients with epalrestat treatment, the observation group patients with epalrestat plus Danhong injection treatment, the treatment effect of two groups were discussed. Results: The effective rate of treatment in observation group was 93.33%, which was higher than that of control group (73.33%). There was significant difference between two groups (P <0.05). After treatment, sensory nerve conduction velocity (SNCV), motor nerve conduction (MNCV) were higher than the control group, the difference was statistically significant (P <0.05). Conclusion: In patients with DPN, the combination of epalrestat and Danhong injection can effectively relieve the clinical symptoms, improve the motor and sensory conduction velocity and speed up the recovery.