论文部分内容阅读
目的探讨氟康唑在复发性假丝酵母菌性阴道炎中的疗效及安全性,以了解其在该病治疗中的价值。方法选取2009年2月-2011年12月于医院采用制霉菌素治疗的62例复发性假丝酵母菌性阴道炎患者为对照组,同期采用氟康唑治疗的62例患者为观察组,将两组治疗后2、4、8周的治愈率、不良反应发生率和3、6个月的复发率进行统计比较。结果观察组治疗后2、4、8周的治愈率分别为88.71%、95.16%和98.39%,均高于对照组的80.65%、85.48%和90.32%,3、6个月的复发率分别为1.61%和3.23%,均低于对照组的6.45%和9.68%,差异有统计学意义(P<0.05),而两组不良反应发生率比较,差异无统计学意义。结论氟康唑在治疗复发性假丝酵母菌性阴道炎中的疗效及安全性均值得肯定。
Objective To investigate the efficacy and safety of fluconazole in recurrent Candida vaginitis to understand its value in the treatment of the disease. Methods 62 patients with recurrent Candida vaginitis treated with nystatin in the hospital from February 2009 to December 2011 were selected as the control group. 62 patients treated with fluconazole during the same period were selected as observation group. The cure rates, adverse reaction rates and recurrence rates at 3, 6 months after 2, 4, and 8 weeks of treatment in both groups were compared statistically. Results The cure rates of the observation group at 2, 4, 8 weeks after treatment were 88.71%, 95.16% and 98.39%, respectively, which were higher than 80.65%, 85.48% and 90.32% of the control group respectively. The recurrence rates at 3 and 6 months were 1.61% and 3.23%, respectively, which were lower than 6.45% and 9.68% in the control group (P <0.05). There was no significant difference in the incidence of adverse reactions between the two groups. Conclusion The efficacy and safety of fluconazole in the treatment of recurrent Candida vaginitis are worthy of positive confirmation.