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目的探讨甲状腺肿患者尿液及血清中碘、双酚A(BPA)的检测意义。方法选取于2014年11月~2015年11月就诊于本院及宁波市第二医院的甲状腺肿患者92例,并选取健康志愿者70例。对甲状腺肿患者及健康志愿者尿液及血清中碘、BPA进行检测。比较各组间尿液及血清中碘、BPA含量的差异。结果甲状腺肿患者尿液中碘水平明显高于健康志愿者,血清中碘水平明显低于健康志愿者(P<0.05)。甲状腺肿患者血清及尿液中BPA水平均低于健康志愿者(P<0.05)。甲状腺肿患者血清与尿液中碘不存在相关性,血清与尿液中BPA也不存在相关性,但尿液中碘与尿液中BPA存在相关性(P<0.01)。结论血清及尿液中碘、BPA水平检测对甲状腺肿预防具有借鉴作用。
Objective To investigate the detection of iodine and bisphenol A (BPA) in urine and serum of patients with goiter. Methods From November 2014 to November 2015, 92 patients with goiter who visited our hospital and Ningbo No.2 Hospital were selected and 70 healthy volunteers were selected. Urine and serum iodine and BPA in goiter patients and healthy volunteers were detected. The urine and serum iodine and BPA levels were compared between groups. Results The urinary iodine level of goiter patients was significantly higher than that of healthy volunteers, and the level of iodine in serum was significantly lower than that of healthy volunteers (P <0.05). BPA levels in serum and urine of goiter patients were lower than those of healthy volunteers (P <0.05). Serum of goiter patients did not correlate with urine iodine, nor did serum BPA correlate with urine, but there was a correlation between urine iodine and urine BPA (P <0.01). Conclusion The detection of iodine and BPA in serum and urine can be used as a reference for the prevention of goiter.