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本文作者应用放射免疫测定技术对多发性硬化症,病毒性脑膜炎和肿瘤病人的脑脊液免疫球蛋白G,A,M,D及E值进行了定量分析,发现在上述疾患中所有五类脑脊液免疫球蛋白均有明显变化。结果如下: 在25例多发性硬化症病人中,16例(64％)的总蛋白增高,17例的IgG增高,23例(92％)的IgA增高,全部病例的IgD及IgE均降低。在35例推测为病毒感染的无菌性脑膜炎病人中,全部病例的IgM均增高,17例(49％)的IgA增高,而全部病例的IgD均正常。
The authors used radioimmunoassay to quantify cerebrospinal fluid immunoglobulin G, A, M, D, and E values in patients with multiple sclerosis, viral meningitis, and oncology and found that in all of the above conditions, all five cerebrospinal fluid immunizations Globulin have significant changes. The results were as follows: Of 25 patients with multiple sclerosis, 16 (64%) had higher total protein, 17 had higher IgG, 23 (92%) had higher IgA, and all cases had lower IgD and IgE. IgM was elevated in all 35 cases of aseptic meningitis presumed to be virally infected, IgA was elevated in 17 cases (49%), and IgD was normal in all cases.