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作者在1980年到1984年4年间,对以色列和欧洲7个地区再生障碍性贫血(再障)的发病率进行了研究。诊断标准为:外周血象要具备以下3条中至少2条:(1)Hb≤100g/L,或Ht≤30%;(2)Plt≤50×10~9/L;(3)WBC≤3.5×10~9/L,或粒细胞≤1.5×10~9/L。骨髓组织学检查具备以下2点:(1)有核细胞增生低下、全部造血细胞缺如或减少,或者由于红系灶性增生而致细胞增生正常,但一定有粒系和巨核细胞系减少;(2)无明显骨髓纤维化或肿瘤侵润。还应排除因细胞毒药物或放射损伤造成的全血细胞减少。结果:8个地区4年间确诊再障168例,发病率为2.2/百万人/年,其中男性为2.1/百万人/年,女性为2.4/百万人/年。女性发
The author studied the incidence of aplastic anemia (aplastic anemia) in seven regions of Israel and Europe in the four years from 1980 to 1984. Diagnostic criteria: peripheral blood as to have at least two of the following 3: (1) Hb≤100g / L, or Ht≤30%; (2) Plt≤50 × 10 ~ 9 / L; (3) WBC≤3.5 × 10 ~ 9 / L, or granulocytes ≤ 1.5 × 10 ~ 9 / L. Bone marrow histology has the following 2 points: (1) low proliferation of nucleated cells, all of the hematopoietic cells missing or reduced, or due to erythroid focal hyperplasia caused by normal cell proliferation, but there must be a decrease in granulocyte and megakaryocyte lines; (2) no significant myelofibrosis or tumor invasion. It should also be excluded due to cytotoxic drugs or radiation pancytopenia caused by pancytopenia. Results: A total of 168 cases of aplastic anemia were diagnosed in 4 districts over a period of 4 years. The incidence rate was 2.2 / million people / year, of which 2.1 for men / million people / year and 2.4 / million women / year. Female hair