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作者对52名印度服用口服避孕药妇女的免疫状况进行了研究,另有29名不服药妇女作为对照。全部研究对象的年龄为20～30岁,平均身长151.2cm,体重45.2kg,平均血色素为13.2g/dl,无1例低1于8 g/dl,亦均无明显的临床感染。服药者服用8-甲基炔诺酮150μg及炔雌醇30或50μg,连续12～24个月。对全部对象测定下列免疫参数:(1)T淋巴细胞和B淋巴细胞百分比;(2)加入~3H-胸腺嘧啶后测定PHA引起的淋巴细胞转化(PILT);(3)用药组和对照组各取12例测定血
The authors studied the immunological status of 52 women taking oral contraceptives in India, and another 29 uncontrolled women served as controls. All subjects were 20-30 years old with an average body length of 151.2 cm and a body weight of 45.2 kg. The mean hemoglobin was 13.2 g / dl, none of the subjects was lower than 1 and 8 g / dl, and no significant clinical infection was found. Drugs taking 8-methyl norgestrel 150μg and ethinylestradiol 30 or 50μg for 12 to 24 months. The following immune parameters were determined for all subjects: (1) percentages of T lymphocytes and B lymphocytes; (2) measurement of PHA-induced lymphocyte transformation (PILT) after addition of ~ 3H-thymidine; Take 12 cases of blood test