论文部分内容阅读
目的观察未治疗的2型糖尿病患者,应用胰岛素泵持续皮下注射(CSII)及胰岛素每天多次皮下注射(MSII)的临床疗效。方法采用前瞻性对照研究,将39例初治2型糖尿病患者随机分为胰岛素泵治疗组和胰岛素4次/d皮下治疗组。比较治疗2周后两组空腹血糖、餐前血糖、餐后2h血糖、胰岛素日剂量、低血糖、严重低血糖事件的发生情况。结果应用CSII组与MSII组治疗后比较,空腹血糖、餐后2h血糖、胰岛素日剂量均有差异,P<0.05,低血糖发生次数为8对14,严重低血糖发生次数1对3。结论与MSII相比,CSII治疗使全天血糖控制更理想,胰岛素日剂量用量小,低血糖及严重低血糖发生次数明显低于前者。
Objective To observe the clinical effect of continuous subcutaneous injection of insulin pump (CSII) and subcutaneous injections of insulin (MSII) on untreated type 2 diabetic patients. Methods A prospective controlled study of 39 newly diagnosed type 2 diabetic patients was randomly divided into insulin pump treatment group and insulin 4 times / d subcutaneous treatment group. The incidences of fasting blood glucose, pre-prandial blood glucose, postprandial blood glucose 2h, daily insulin dosage, hypoglycemia and severe hypoglycemia were compared between the two groups after 2 weeks of treatment. Results After applying CSII and MSII, fasting blood glucose, postprandial 2h blood glucose and daily insulin dosage were all different (P <0.05). The incidence of hypoglycemia was 8 to 14 and severe hypoglycemia was 1 to 3. Conclusion Compared with MSII, CSII treatment makes the control of blood glucose more ideal, the daily dose of insulin is small, the incidence of hypoglycemia and severe hypoglycemia is obviously lower than the former.