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核苷类逆转录酶抑制剂可以降低HIV 1母婴传播率 ,齐多夫定 (Zidovudine)常用来预防妊娠期HIV 1的母婴传播 ,作者研究了产前预防治疗后 ,齐多夫定对儿童线粒体的毒性作用。方法 3779对母婴 ,其中 1 75 4例母亲在妊娠期使用过齐多夫定或其它药物。作者分析联用
Nucleoside reverse transcriptase inhibitors reduce the rate of mother-to-child transmission of HIV-1, and Zidovudine is commonly used to prevent mother-to-child transmission of HIV-1 during pregnancy. The authors studied the effect of zidovudine on prenatal prophylaxis Children’s mitochondrial toxicity. Method 3779 For mother and child, 1,754 mothers used zidovudine or other medications during pregnancy. Author analysis combined