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抗纤溶疗法可能引起血栓栓塞性并发症已为多数作者所报导,但迄今尚未见涉及合成抗纤溶剂对中枢神经系统(CNS)、脑血流量(CBF)及颅内压力(ICP)的可能作用之报导.作者旨在指出止血环酸(AMCA)对实验动物之脑电图、大脑皮质血流及ICP有显著作用,以提醒注意.作者对15只重2.0-4.0公斤的成年雌猫进行双额区脑电图,右中侧裂上回的皮质血流(热电偶法)、ICP(硬膜外)及血压(经股动脉插管)的监护测定.在监护上述参数下,给15只猫静脉注射10%AMCA(剂量为1、5、20、100毫克/公斤),一次或多次注射.给3只猫以4%AMCA(1毫克/公斤)溶
Anti-fibrinolytic therapy may cause thromboembolic complications have been reported by most authors, but so far have not been involved in the synthesis of anti-fibrinolytic agents on the central nervous system (CNS), cerebral blood flow (CBF) and intracranial pressure (ICP) may The aim of the authors is to point out that tranexamic acid (AMCA) has a significant effect on EEG, cerebral cortical blood flow, and ICP in experimental animals, to alert attention. The authors evaluated 15 adult female cats weighing 2.0-4.0 kg (Epidural), ICP (epidural), and blood pressure (via femoral artery cannulation) in the etanercept, double-area EEG, Cats were injected intravenously with 10% AMCA (1, 5, 20, 100 mg / kg) in one or more injections, and 3 cats were treated with 4% AMCA