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煤焦沥青(CTP)诱发大鼠肺癌已有动物实验证实[1,2],焦炉工肺癌在我国已列入职业肿瘤。体内自由基损伤理论认为,许多毒物在体内可通过激发自由基反应,加剧细胞膜不饱和脂肪酸脂质过氧化(LPO)进程[3]。过氧化脂质的大量形成及其代谢毒物在细胞内聚集、降解
Coal tar pitch (CTP) -induced lung cancer in rats has been confirmed by animal experiments [1,2], coke oven lung cancer in our country has been included in the occupational tumor. The theory of free radical damage in vivo suggests that many toxicants exacerbate the process of lipid peroxidation (LPO) in the plasma membrane by stimulating free radical reactions [3]. A large number of lipid peroxidation and metabolism of toxic accumulation in the cell, degradation