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目的:比较胰岛素泵持续皮下输注胰岛素(CSII)与多次胰岛素皮下注射(MSII)治疗初发2型糖尿病的疗效与安全性。方法:对空腹血糖>10 mmol/L的60例初发2型糖尿病患者随机分组;胰岛素泵持续注射胰岛素治疗组(CSII组)30例,多次皮下注射胰岛素治疗组(MSII组)30例,比较两种方法治疗前后血糖、胰岛素用量、血糖达标所需时间以及低血糖发生率。结果:CSII组在血糖降至正常所需时间、胰岛素用量及低血糖发生率上均明显优于MSII组(P<0.05)。结论:胰岛素泵强化治疗初发2型糖尿病是一有效的治疗方法。
Objective: To compare the efficacy and safety of insulin pump continuous subcutaneous infusion of insulin (CSII) and multiple insulin subcutaneous injection (MSII) in the treatment of newly diagnosed type 2 diabetes. Methods: Sixty patients with newly diagnosed type 2 diabetes with fasting plasma glucose> 10 mmol / L were randomly divided into three groups: 30 patients in continuous insulin pump group (CSII group), 30 in insulin subcutaneous injection group (MSII group) Compare the two methods before and after treatment of blood glucose, insulin dosage, blood glucose compliance time and the incidence of hypoglycemia. Results: The CSII group was significantly better than the MSII group in the time required for blood glucose to drop to normal, the amount of insulin and the incidence of hypoglycemia (P <0.05). Conclusion: Insulin pump intensive treatment of newly diagnosed type 2 diabetes is an effective treatment.