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用中药明目增视Ⅰ号对家兔进行体外平滑肌解痉实验研究。结果表明,明目增视Ⅰ号可明显减弱正常状态的平滑肌收缩幅度和频率;并能对抗乙酰胆碱而致的病理性平滑肌痉挛,使处于兴奋状态的平滑肌收缩频率频幅正常。认为明目增视Ⅰ号治疗青少年近视眼的机理主要为解除睫壮肌痉挛,达到矫正近视,提高视力的作用。
EXPERIMENTAL STUDY ON VASCULAR SMOOTH MUSCULAR STIMULATION IN RABBITS WITH CHINESE MEDICINE. The results showed that the eyesight increased as No. Ⅰ can significantly reduce the normal state of smooth muscle contraction amplitude and frequency; and can antagonize the acetylcholine-induced pathological smooth muscle spasm, so excited in the normal frequency of smooth muscle contraction frequency. That the eyesight as No. I treatment of juvenile myopia mechanism is mainly to lift the spasm of ciliary muscle, to achieve correction of myopia, improve visual acuity.