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目的分析在重度窒息新生儿的早期干预过程中使用黄芪注射液所引起的脑损伤程度变化。方法选择30例抢救成功的重度窒息新生儿,依照抢救顺序划分黄芪组和对照组,每组15例,对照组积极地给予对症治疗并使用临床常规用药(胞二磷胆碱等),黄芪组在对照组的治疗措施的基础上,在早期加用黄芪注射液。对比两组脑损伤程度变化(包括HIE程度、死亡比例等)。结果黄芪组与对照组的HIE程度、死亡比例,差异无统计学意义(P>0.05),两组惊厥比例、神经评分>35分所占比例、通气比例比较,差异有统计学意义(P<0.05)。结论在重度窒息新生儿的早期干预过程中使用黄芪注射液有助于降低脑损伤程度,改善大脑供血、供氧。
Objective To analyze the changes of brain injury caused by astragalus injection in the early intervention of severe asphyxia neonates. Methods Thirty newborns with severe asphyxia who were rescued successfully were divided into three groups according to the order of rescue: 15 cases in each group, and the control group was given symptomatic treatment actively and used routine clinical medicine (Citicoline, etc.), Astragalus group In the control group based on the treatment measures, early use Astragalus injection. The level of brain injury was compared between the two groups (including the degree of HIE, the proportion of death, etc.). Results There was no significant difference in HIE level and death rate between Astragalus membranaceus group and control group (P> 0.05). There was significant difference between the two groups in the proportion of convulsion, neurological score> 35 and ventilation ratio (P < 0.05). Conclusion Astragalus injection during the early intervention of severe asphyxia neonatorum can reduce the degree of brain injury and improve the cerebral blood supply and oxygen supply.