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地中海或库理氏贫血属于体质性溶血性贫血,本病为红细胞结构的严重改变所致,此与血红蛋白合成紊乱有关。属于复杂的血红蛋白病即为复杂的分子疾病。早已认为本病的发生与红细胞内存在先天性异常的血红蛋白(HbF,HbA_2)有关。而根据近年来的研究,认为在某些溶血性贫血的溶血作用解释,其中包括有地中海贫血,6-磷酸葡萄糖脱氢酶(Glucose-6-Phosphate Dehydrogenase)缺乏有一定意义。作者报告2例,临床上有典型之地中海贫血的表
Mediterranean or Coarse anemia is a constitutional hemolytic anemia, the disease is caused by a serious change in the structure of red blood cells, which is related to hemoglobin synthesis disorders. Belong to the complex hemoglobin disease is a complex molecular disease. Has long been thought that the occurrence of this disease and the presence of erythrocyte congenital abnormal hemoglobin (HbF, HbA_2) related. According to recent studies, hemolysis in some hemolytic anemia is considered to explain, including thalassemia, lack of 6-phosphate glucose dehydrogenase (Glucose-6-phosphate dehydrogenase) is of some significance. The authors report 2 cases of clinically typical thalassemia tables