Physiological effects of amyloid precursor protein and its derivatives on neural stem cell biology a

• 作 者: Raquel Coronel Charlotte Palme
• 机 构: UnidaddeRegeneració,nNeural
• 出 处: 中国神经再生研究:英文版
• 发表日期: 2019年10期
• 关键词: AMYLOID precursor protein APP SOLUBLE APP alpha SOLUBLE APP BETA AMYLOID BETA pe
• 基金项目: supported by grants from the Ministerio de Ciencia e Innovación-Instituto de Salud Carlos Ⅲ(PI-10/00291 and MPY1412/09),Ministerio de Economía y Competitividad(SAF2015-71140-R),Comunidad de

The pathological implication of amyloid precursor protein(APP)in Alzheimer’s disease has been widely documented due to its involvement in the generation of amyloid-β peptide.However,the physiological functions of APP are still poorly understood.APP is con