TRAF7 enhances degradation of ubiquitinated KLF4 to promote hepatocellular carcinoma progression

• 作 者: Huan He Zhiyuan Wu Sheng Li Do
• 机 构: CancerHospital
• 出 处: 癌症生物学与医学:英文版
• 发表日期: 2018年S01期
• 关键词: TRAF7 enhances DEGRADATION

Objective:The tumor necrosis factor receptor-associated factor 7(TRAF7)is one of the components of the tumor necrosis factor alpha(TNF-α)/nuclear factor kappa B(NF-κB)pathway and a putative E3-ubiquitin ligase.This study aims to explore the biologic effec