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目的了解男、女性泌尿生殖道感染患者解脲支原体(Uu)和人型支原体(Mh)感染及耐药情况。方法采用支原体(Uu/Mh)分离培养药敏试剂盒(微生物检验法),对3 692例泌尿生殖道感染患者分泌物进行支原体培养及药敏试验。结果 3 692例标本中支原体培养阳性2 401例,检出率为65.0%,其中单纯Uu阳性率为48.6%,单纯Mh阳性率2.6%,Uu和Mh混合阳性率13.8%。在1 635例男性标本中支原体培养阳性772例,阳性率47.2%,2 057例女性标本中支原体培养阳性率1 629例占79.2%,女性支原体阳性率明显高于男性,两者差异有统计学意义(P<0.01)。药敏结果显示,支原体对交沙霉素、强力霉素和美满霉素较为敏感;对罗红霉素耐药率最高,其次氧氟沙星、环丙沙星和左氧氟沙星。结论泌尿生殖道支原体感染主要以Uu为主,对各种抗菌药物均有一定的耐药性,临床应对患者尽早进行支原体培养及药敏试验,根据药敏试验选用敏感的抗菌药物。
Objective To understand the infection and drug resistance of ureaplasma urealyticum (Uu) and Mycoplasma hominis (Mh) in male and female genitourinary tract infections. Methods Mycoplasma (Uu / Mh) isolates and culture kit were used to detect the mycoplasma in 3 692 patients with genitourinary tract infection. Results A total of 2 401 positive mycoplasma were detected in 3 692 specimens. The detection rate was 65.0%. The positive rate of Uu was 48.6%, the positive rate of Mh was 2.6% and the positive rate of Uu and Mh was 13.8%. The positive rate of mycoplasma culture in 1 635 male specimens was 772, the positive rate was 47.2%. The positive rate of mycoplasma culture in 1 057 female specimens was 1629 (79.2%). The positive rate of mycoplasma in women was significantly higher than that in males Significance (P <0.01). Drug susceptibility results showed that mycoplasma was more sensitive to jasminemycin, doxycycline and minocycline, and had the highest resistance to roxithromycin, followed by ofloxacin, ciprofloxacin and levofloxacin. Conclusions UU is the main genitourinary tract infection of U genital tract. It has certain resistance to various antimicrobial agents. Mycoplasma culture and drug sensitivity test should be conducted as soon as possible in patients with clinical response. Sensitive antimicrobial agents should be selected according to drug sensitivity test.