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目的：探讨甲状腺摄碘率＜30%甲亢患者131I的治疗疗效。方法：2009年1月-2011年3月收治经甲亢131I治疗患者844例，将甲状腺摄碘率＜30%的患者作为试验组，而将甲状腺摄碘率＞30%的患者作为对照组进行治疗，并对治疗后的甲亢治愈率和甲减发生率进行分析。结果：在经过6个月的治疗后，两组的甲低发生率和治愈率并无明显的差异。结论：131I治疗适用于低甲状腺摄碘率甲亢患者且疗效显著。“,”Objective:To investigate the efficacy of 131I in the treatment of hyperthyroidism patients whose iodine uptake rate<30%.Methods:844 cases with hyperthyroidism who had 131I therapy were selected from January 2009 to March 2011.The thyroid iodine uptake rate30% patients as the control group. We analyzed the cure rate of hyperthyroidism and the occurrence rate of hypothyroidism after the treatment.Results:After 6 months of treatment,the hypothyroidism occurrence rate and cure rate of two groups had no obvious difference. Conclusion:131I treatment is suitable for low iodine uptake rate of thyroid hyperthyroidism patients and its effect is significant.