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颅底肿瘤解剖部位深在,颅底血管结构复杂,术中对血管的牵拉以及蛛网膜下腔出血等因素常造成术后脑血管痉挛(CVS)的发生。CVS的发病机制复杂,易导致迟发性神经功能障碍,是术后病人致残和死亡的重要原因。目前常用的诊断CVS的方法是数字减影血管造影(DSA)和经颅多普勒超声(TCD)。治疗主要用钙拮抗剂和自由基清除剂,而预防其发生的关键在于完善细致的术前准备和科学轻柔的术中操作。
Skull base tumor deep in the anatomy, skull base vascular complex structure, intraoperative vascular traction and subarachnoid hemorrhage and other factors often cause postoperative cerebral vasospasm (CVS). The pathogenesis of CVS is complex, easily lead to delayed neurological dysfunction, is an important cause of postoperative disability and death of patients. Currently used methods for the diagnosis of CVS are digital subtraction angiography (DSA) and transcranial Doppler ultrasound (TCD). The main treatment with calcium antagonists and free radical scavengers, and the key to preventing its occurrence is to improve the meticulous preparation and preoperative science gentle operation.