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目的探讨阿奇霉素治疗小儿支气管炎急性发作的临床疗效。方法选取全南县人民医院2015年12月—2016年12月收治的支气管炎急性发作患儿60例,将所有患儿随机分为对照组与试验组,每组30例。对照组患儿予以头孢曲松钠治疗,试验组患儿予以阿奇霉素治疗,比较两组患者临床疗效、临床症状消失时间及不良反应发生情况。结果试验组患儿临床总有效率为96.7%,高于对照组的80.0%,咳嗽、气喘、咳痰消失时间短于对照组,不良反应发生率为3.3%,低于对照组的26.8%(P<0.05)。结论阿奇霉素治疗小儿支气管炎急性发作的临床疗效确切,可有效改善患儿临床症状,且安全性较高。
Objective To investigate the clinical efficacy of azithromycin in the treatment of acute episodes of infantile bronchitis. Methods 60 patients with acute attack of bronchitis admitted from December 2015 to December 2016 in Quannan County People’s Hospital were enrolled. All children were randomly divided into control group and experimental group with 30 cases in each group. Patients in the control group were treated with ceftriaxone sodium. Patients in the experimental group were treated with azithromycin. The clinical efficacy, the disappearance of clinical symptoms and the incidence of adverse reactions were compared between the two groups. Results The total clinical effective rate was 96.7% in the experimental group, higher than 80.0% in the control group. The disappearance time of cough, asthma and expectoration was shorter than that of the control group. The incidence of adverse reactions was 3.3%, which was lower than that of the control group (26.8% P <0.05). Conclusion Azithromycin treatment of acute bronchitis in children with clinical curative effect is exact, can effectively improve the clinical symptoms of children with high safety.