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目的探究青春期功血采用米非司酮治疗的临床疗效以及对患者内分泌功能的影响。方法 72例青春期功血患者,按照入院顺序分为对照组和治疗组,各36例,对照组患者采用安宫黄体酮治疗,治疗组患者采用米非司酮治疗,观察比较两种治疗方法的应用效果。结果治疗组治疗总有效率为94.4%显著高于对照组的77.8%,差异有统计学意义(P<0.05);治疗后两组患者孕酮(P)和雌二醇(E2)等指标水平均较治疗前降低,差异有统计学意义(P<0.05),且治疗组患者P、E2水平降低程度优于对照组,差异有统计学意义(P<0.05)。结论青春期功血采用米非司酮治疗,可有效止血并改善患者内分泌功能,值得临床推广应用。
Objective To investigate the clinical efficacy of adolescent dysfunctional uterine bleeding with mifepristone and its effect on the endocrine function of patients. Methods Seventy-two patients with adolescent dysfunctional uterine bleeding were divided into control group and treatment group according to admission sequence, 36 cases in each group. Patients in the control group were treated with An forgoing progesterone. Patients in the treatment group were treated with mifepristone and compared with two treatment methods Application effect. Results The total effective rate of the treatment group was 94.4%, which was significantly higher than that of the control group (77.8%) (P <0.05). The levels of progesterone (P) and estradiol (E2) (P <0.05), and the level of P and E2 in the treatment group was lower than that in the control group, the difference was statistically significant (P <0.05). Conclusion Adolescent dysfunctional uterine bleeding with mifepristone treatment can effectively stop bleeding and improve the endocrine function of patients, worthy of clinical application.