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目的探讨缺血性脑小血管病危险因素及临床表现的相关分析。方法收集确诊的缺血性脑小血管病患者114例作为观察对象,同期114例非小血管病的缺血性卒中患者作为对照组;对2组的发病危险因素和临床表现进行分析、总结。结果观察组中高血压、糖尿病、高脂血症、血同型半胱氨酸、吸烟、酗酒等因素高于对照组,差异有统计学意义(P<0.05)。小血管病变导致的脑梗死患者中临床表现有认知功能障碍、血管性痴呆患者明显较多,与对照组比较,差异有统计学意义(P<0.05)。结论长期高血压、糖尿病、高脂血症、高同型半胱氨酸血症、吸烟、酗酒是引起脑小血管病的危险因素,缺血性小血管病变多为腔隙性脑梗死,在临床上表现为认知功能障碍和血管性痴呆的患者较多,故控制上述危险因素是降低脑小血管病发病率及预防血管性痴呆的重要手段。
Objective To investigate the risk factors and clinical manifestations of ischemic cerebrovascular disease. Methods A total of 114 patients with ischemic cerebrovascular disease were collected from 114 patients with ischemic stroke. The risk factors and clinical manifestations of the two groups were analyzed and summarized. Results In the observation group, the factors such as hypertension, diabetes, hyperlipidemia, blood homocysteine, smoking, alcoholism were higher than those in the control group, with statistical significance (P <0.05). Clinical manifestations of patients with cerebral infarction caused by small blood vessel disease were cognitive dysfunction, vascular dementia patients were significantly more, compared with the control group, the difference was statistically significant (P <0.05). Conclusion Long-term hypertension, diabetes mellitus, hyperlipidemia, hyperhomocysteinemia, smoking and alcohol abuse are the risk factors of cerebrovascular disease. Most of ischemic small vessel disease is lacunar infarction. In the clinical On the performance of cognitive impairment and vascular dementia patients are more, so the control of these risk factors is to reduce the incidence of cerebrovascular disease and prevention of vascular dementia an important means.