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微卫星ＤＮＡ广泛分布于基因组中。微卫星不稳定性、误配修复与结直肠癌发生的关系的研究已取得进展，结直肠癌的肿瘤细胞具有遗传不稳定性，表现为微卫星不稳定性，揭示了一个肿瘤发生的新机制。目前检测微卫星不稳定性的方法已较成熟，可用于临床及实验室研究
Microsatellite DNA is widely distributed in the genome. The research on the relationship between microsatellite instability, mismatch repair and the occurrence of colorectal cancer has progressed. The tumor cells of colorectal cancer are genetically unstable and show microsatellite instability, revealing a new mechanism of tumorigenesis. . The current method for detecting microsatellite instability has matured and can be used for clinical and laboratory research.