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本病是一种小脑肿瘤,常发生于蚓部,可扩展至第四脑室和小脑半球,还常发生蜘蛛网膜下腔种植,甚至颅外转移,治疗后最常见的复发部位是颅后窝,随后可发生脊髓种植。外科治疗对本病疗效甚微,加上局部放疗,稍有改善,只是最近大剂量放疗(颅后窝4500~5000rad,脊柱中轴3000 rad)才将五年存活率提高到30~50%。尽管如此,患者最后仍死于复发。本文报告联合化疗对复发者的疗效。本组5例手术+放疗后之患儿,经临床症状和其他检查证实为本病复发,复发部位均为颅后窝,1例还有脊髓管。年龄3~15岁,男4,女1。化疗期间每
The disease is a cerebellar tumor, often occurs in the vermis, can be extended to the fourth ventricle and cerebellar hemispheres, but also often occurs subarachnoid planting, or even extracranial metastasis, the most common site of recurrence after treatment is the posterior fossa , Followed by spinal cord implantation. Surgical treatment of the disease with little effect, with local radiotherapy, a slight improvement, only the recent high-dose radiotherapy (posterior fossa 4500 ~ 5000rad, spinal axis 3000rad) only five-year survival rate increased to 30 to 50%. In spite of this, the patient eventually dies of recurrence. This article reports the efficacy of combination chemotherapy in relapsers. The group of 5 patients after surgery + radiotherapy in children, clinical symptoms and other tests confirmed the recurrence of this disease, recurrence sites are posterior fossa, spinal cord in 1 case. Age 3 to 15 years old, male 4, female 1. During chemotherapy each