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业已证明淀粉样变性是长期血透患者的严重并发症,与透析相关的淀粉样变性的流行病学仍不清楚,有报道β_2微球蛋白(β_2M)在透析患者的血液、组织液和滑膜液中积聚,在少数患者还可在心脏、肾脏和前列腺内沉积。本文测定慢性肾衰患者透析前、后的血β_2M 浓度,其中常规血透30例;高流量(HF)血透35例;首次血透5例;持续性不卧床腹膜透析(CAPD)13例;成功肾移植3例。β_2M采用放免法测定。
It has been reported that amyloidosis is a serious complication of long-term hemodialysis patients, and the epidemiology of amyloidosis associated with dialysis remains unclear. It has been reported that β_2-microglobulin (β_2M) is highly expressed in dialysis patients’ blood, tissue fluid and synovial fluid In a small number of patients can also be deposited in the heart, kidney and prostate. In this paper, the determination of serum β_2M concentration before and after dialysis in patients with chronic renal failure, including 30 cases of conventional hemodialysis; high flow (HF) hemodialysis in 35 cases; hemodialysis in 5 cases; continuous ambulatory peritoneal dialysis (CAPD) in 13 cases; Three cases of successful kidney transplantation. β_2M using radioimmunoassay.